Abstract: A framework of multi-agent joint firefighting and rescue operation was proposed by applying the multi-agent theory and technology to studies on joint firefighting and rescue operation. It can realize information exchange between the commanders and display the interacted course of operation. Based on the description of command agent, operation agent and environment agent in the system, interaction rules between the agents and between the agent and environment were defined to describe the system's interrelation, a multi-agent coordination algorithm was given, and a joint firefighting and rescue simulation model was built. At last, a simulation is made on SWARM software to validate the proposed model.