Lubricating Behaviour of Hyaluronic Acid in Artificial Articular Materials
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摘要: 配合人工軟骨材料的研究,探討透明質酸(HA)作為摩擦副的人工滑液時的潤滑性能.在PVA-H/316L,PVA-H/PVA-H兩類摩擦副上,利用錐板式粘度計、改進后的振子式摩擦儀和M2000型磨損試驗機,測定了不同質量分數的HA溶液的流變性質、摩擦性能和磨損性能.結果表明,HA溶液一定程度上具有天然滑液的流變性質,并有效地降低了摩擦副的摩擦磨損,其對PVA-H/PVA-H摩擦副潤滑作用更佳,且0.75%(質量分數)的HA溶液表現出優于體積分數為30%小牛血清的潤滑性能,可認為HA是很有前途的人工滑液.Abstract: Supporting the study of artificial articuar cartilage materials, the research and development of an artificial synovial fluid of Hyaluronic acid (HA) was carried out. With two lubricated sliding pairs, PVAH/316L and PVA-H/PVA-H, an modified oscillator-type tri-biometer and M-2000 wear test machine were used to detemine the rehological properties and lubricating behaviour of a series of HA solution.The experimental results showed that the solution of HA had the rehological properties similaring to the natural synovial fluid to a cehain eXtellt, and decreased the ffiction and wear of tWo kinds of lubricatCd sliding pairs, also it rendered abetter 1ubricating effection on PVA-unVA-H than on PVA-H/3 l6L. The sofution of HA with O.75% (massfraction) showed a better lubricating behaviour than 30% (volumic fraction) Bovine Serum. So HA solutionwould be a promising Anficial synovial fluid.
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Key words:
- hyaluronic acid /
- artificial synovial fluid /
- friction /
- wear
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